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HEP-G2

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Cat.No.
CSC-C0313
Description
This cell line was isolated from a liver biopsy of a male Caucasian aged 15 years, with a well differentiated hepatocellular carcinoma. The cells secrete a variety of major plasma proteins e.g. albumin, alpha2-macroglobulin, alpha 1-antitrypsin, transferrin and plasminogen. The cells demonstrate decreased expression of apoA-I mRNA and increased expression of catalase mRNA in response to gramoxone (oxidative stress). There is no evidence of a Hepatitis B virus genome in this cell line.
Tissue of Origin
Liver
Organism
Homo sapiens, human
Source
Liver
Recommended Medium
Culture Properties
Adherent
Morphology
epithelial-like
STR DNA Profile
D3S1358: 15,16
vWA: 17
FGA: 22,25
Amelogenin: X,Y
TH01: 9
TPOX: 8,9
CSF1P0: 10,11
D5S818: 11,12
D13S317: 9,13
D7S820: 10
Karyotype
modal number = 55 (range = 50 to 60); has a rearranged chromosome 1
Applications
The Hep-G2 cell line can be used for hepatocyte function study and specific protein expression, it also can be used as a suitable transfection host.
Quality Control
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
liquid nitrogen vapor phase
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
Customer Support & Price Inquiry
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