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HEP-G2

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Cat.No.
CSC-C0313
Description
This cell line was isolated from a liver biopsy of a male Caucasian aged 15 years, with a well differentiated hepatocellular carcinoma. The cells secrete a variety of major plasma proteins e.g. albumin, alpha2-macroglobulin, alpha 1-antitrypsin, transferrin and plasminogen. The cells demonstrate decreased expression of apoA-I mRNA and increased expression of catalase mRNA in response to gramoxone (oxidative stress). There is no evidence of a Hepatitis B virus genome in this cell line.
Tissue of Origin
Liver
Organism
Homo sapiens, human
STR DNA Profile
D3S1358: 15,16
vWA: 17
FGA: 22,25
Amelogenin: X,Y
TH01: 9
TPOX: 8,9
CSF1P0: 10,11
D5S818: 11,12
D13S317: 9,13
D7S820: 10
Karyotype
modal number = 55 (range = 50 to 60); has a rearranged chromosome 1
Source
Liver
Culture Properties
Adherent
Morphology
epithelial-like
Recommended Medium
Quality Control
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
liquid nitrogen vapor phase
Application
The Hep-G2 cell line can be used for hepatocyte function study and specific protein expression, it also can be used as a suitable transfection host.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
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