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BV-173

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Cat.No.
CSC-C0203
Description
The BV173 cell line was derived from the peripheral blood of a 45-year-old man with chronic myeloid leukemia (CML) in blast crisis in 1980; contains the t(9;22) leading to BCR-ABL1 e13-a2 (b2-a2) fusion gene.
Organism
Human
STR DNA Profile
Amelogenin: X,X
CSF1PO: 11,12
D13S317: 8,10
D16S539: 11,13
D5S818: 10,12
D7S820: 10,11
THO1: 6,9.3
TPOX: 8,10
vWA: 16
D3S1358: 16,17
D21S11: 30,32
D18S51: 12,16
Penta E: 12,16
Penta D: 11
D8S1179: 11,12,13
FGA: 20,24
Karyotype
t(9; 22) Modal Number: 2n=46
Source
Blood
Culture Properties
suspension
Morphology
Undifferentiated blast cells
Quality Control
Fluorescence (DAPI) test: negative; Mycoplasma specific PCR: negative; Bacteria
specific PCR: negative
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 6 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Reference
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
Design, Synthesis, and Evaluation of Dasatinib-Amino Acid and Dasatinib-Fatty Acid Conjugates as Protein Tyrosine Kinase Inhibitors Authors: Tiwari R K, Brown A, Sadeghiani N, et al.
The ChemMedChem, 2017, 12(1): 86-99.
New Mouse Models to Investigate the Efficacy of Drug Combinations in Human Chronic Myeloid Leukemia Authors: Lin H, Woolfson A, Jiang X.
The Chronic Myeloid Leukemia: Methods and Protocols. 2016: 187-205.
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