RELM-β (Resistin-like molecule beta/FIZZ2) is an 18 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELM beta, and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver (Rajala, M. et al. J. Clin. Invest. Vol. 111, 225-230 (2003)). Interestingly the molecular structure of RELM beta is highly homologous to that of the adipose-derived cytokine Resistin and RELM beta. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C- X10-C-X-C-X-C-X9-C-C. Recombinant murine RELM beta is an 18.0 kDa, consisting of two 83 amino acid residue chains.
Mouse Retnlb expressed in E.coli
CAT# CSC-CTK0771-25 (25 μg); CAT# CSC-CTK0771-125 (125 μg)
Greater than 97% as determined by SDS-PAGE and HPLC analysis.
Sterile-filtered and lyophilized with no additives.
Please centrifuge product briefly before opening the vial. The lyophilized rMu RELM-beta should be reconstituted in sterile, ultra-pure water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
Storage & Stability
The lyophilized protein is best stored desiccated at -20°C. Reconstituted rRELM beta should be used immediately or stored long-term in undiluted working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.