Parathyroid Hormone-like related Protein (PTHrP) is a member of the Parathyroid hormone family that is expressed in the mammary gland. It is known as a potent inhibitor of chondrocyte maturation. PTHrP is expressed by periarticular perichondrial cells and exerts its biological activity on PP-R expressing cells. During endochondral bone development PTHrP plays a major role in suppressing the onset of hypertrophic differentiation. It is also responsible for most cases of humoral hypercalcemia of malignancy. Recombinant Human PTHrP is a 9.8 kDa protein consisting of 86 amino acid residues.
Human PTHLH expressed in E.coli
CAT# CSC-CTK0505-10 (10 μg); CAT# CSC-CTK0505-50 (50 μg)
Greater than 98% as determined by SDS-PAGE and HPLC analysis.
Less than 1 EU/μg.
The sterile filtered solution was lyophilized from 0.5 x PBS, pH 7.1.
Please centrifuge product before opening vial. The lyophilized powder should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
Storage & Stability
The lyophilized protein, though stable at room temperature, is best stored desiccated at -20°C. Reconstituted PTHrP should be stored in working aliquots at -20°C. Avoid repeated freeze / thaw cycles.
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