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ActoFactor™ Recombinant Human CD34 molecule

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Cat.No.
CSC-CTK0306
Description
CD34 is a cell surface antigen formerly known as hemopoietic progenitor cell antigen-1. CD34 is expressed selectively on human hematopoietic progenitor cells. The biological function of CD34 is still unknown. It is used as a surface marker for very early hematopoietic stem cells. Cells expressing CD34 respond to SCF (stem cell factor ) and LIF in the presence of colony stimulating factors and these factors can induce myeloid differentiation in these cells. The effects of some growth factors on cells expressing CD34 are counteracted by IP-10, a factor the expression of which is induced by IFN-gamma. The proliferation of human CD34 cells is stimulated also by IL- 11, and IL11 synergises with SCF, IL-3, and GM-CSF. In the presence of human IL-17, fibroblasts can sustain the proliferation of CD34 hematopoietic progenitors and their preferential maturation into neutrophils.
Species
Human
Product Overview
Human CD34 expressed in E.coli
Molecular Mass
40 kDa
Size
CAT# CSC-CTK0306-2 2 μg; CAT# CSC-CTK0306-10 (10 μg)
Expression System
E.coli
Purity
Greater than 90% as determined by SDS-PAGE and HPLC analysis.
Activity
N/A
Endotoxin Level
Less than 1 EU/μg.
Formulation
Sterile-filtered, clear solution. Recombinant prote in at 100 μg/ml in 50 mM Tris-acetate (pH 7.5), 1 mM EDTA and 20% glycerol.
Reconstitution
N/A
Storage & Stability
Please Note: Always centrifuge product briefly before opening vial. Store vial at –20°C to –80°C. When stored at the recommended temperature, this protein is stable for 12 months. Avoid repeated freeze-thaw cycles.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
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