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Email: info@creative-bioarray.com

  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-C0258
  • Description
  • According to Chen TR, 1987, the WiDr cell line is a derivative of the HT-29 cell line. HT29 was isolated from a primary colon adenocarcinoma in a 44-year-old Caucasian female. The cells are negative for Colon Antigen 3 expression, but positive for keratin by immunoperoxidase staining. The cells expressed p53 antigen (the p53 produced has a G-A mutation resulting in Arg-His at position 273). Growth of WiDr cells is inhibited by tumor necrosis factor alpha (TNF Inhibitors of dihydrofolate reductase are highly cytotoxic to WiDr cells). WiDr were also described to express epidermal growth factor (EGF).
  • Recommended Medium
  • SuperCult® WiDr Medium
  • Organism
  • Homo sapiens, human
  • Morphology
  • Epithelial
  • STR DNA Profile
  • Amelogenin: X,X
    CSF1PO: 11,12
    D13S317: 11,11
    D16S539: 11,12
    D5S818: 11,12
    D7S820: 10
    THO1: 6,6
    TPOX: 8,9
    vWA: 17,19
    D3S1358: 15,17
    D21S11: 29,30
    D18S51: 13
    Penta E: 14,16
    Penta D: 11,13
    D8S1179: 10
    FGA: 20,22
  • Culture Properties
  • monolayer, adherent
  • Source
  • Colon
  • Quality Control
  • Tests for mycoplasma, bacteria and fungi were negative
  • Storage and Shipping
  • liquid nitrogen vapor phase
  • Application
  • WiDr can produce carcinoembryonic antigen and are tumorigenic in xenogeneic animals. These cells have been used in studies of anti-tumour agents.

  • Disease
  • Colorectal adenocarcinoma

Citation Guidance:
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Contact Us
    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com