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Adipose-derived mesenchymal stem cells (AMSCs) offer potential as a therapeutic option for clinical applications in musculoskeletal regenerative medicine because of their immunomodulatory functions and capacity for trilineage differentiation. In preparation for a phase I clinical trial using AMSCs to treat patients with osteoarthritis, we carried out preclinical studies to assess the safety of human AMSCs within the intra-articular joint space. Read more >
Expansion of mesenchymal stem cells (MSCs) and maintenance of their self-renewal capacity in vitro requires specialized robust cell culture systems. Conventional approaches using animal derived or artificial matrices and a cocktail of growth factors have limitations such as consistency, scalability, pathogenicity and loss of MSC phenotype. Read more >
Like other fibrotic diseases, the cause of Peyronies disease (PD) is still obscure. Since there is now increasing evidence for the role of Mesenchymal Stem Cells (MSCs) as potential treatment to fibrosis, it is crucial to determine their possible efficacy in the treatment of PD. Areas covered: In this review, the authors summarize the emerging data and published studies regarding the use of SCs for the treatment of PD. Read more >
Mesenchymal stem cells (MSCs) are ideal candidates for treatment of diseases. Amniotic membranes are an inexpensive source of MSCs (AM-MSC) without any donor site morbidity in cell therapy. Adipose tissue derived stem cells (ASCs) are also suitable cells for cell therapy. There is discrepancy in CD271 expression among MSCs from different sources. Read more >
Recent progress in regenerative medicine has suggested that mesenchymal stem cell (MSC)-based therapy is a novel potential cure for diabetes. Betatrophin is a newly identified hormone that can increase the production and expansion of insulin-secreting β-cells when administered to mice. In this study, we evaluated the effect of betatrophin overexpression by human adipose-derived MSCs (ADMSCs) by in vitro experiments, as well as following their transplantation into a mice with streptozotocin (STZ)-induced diabetes. Read more >
Stem cells therapy has been suggested as a promising option for the treatment of acute kidney injury (AKI). This study was performed to compare the abilities of xenogenic transplantation of human adipose stromal vascular fraction (SVF) and adipose-derived mesenchymal stem cells (AdMSCs) to facilitate the recovery of renal function and structure in a rat model of ischemia/reperfusion (IR) induced AKI. Read more >
Studies have confirmed that microgravity, as a mechanical factor, influences both differentiation and function of mesenchymal stem cells. Here we investigated the effects of simulated microgravity on neural differentiation of human adipose-derived stem cells (ADSCs).
Two novel alkaloids named oleraciamide A (1) and oleraciamide B (2) were isolated from Portulaca oleracea L., and spectroscopic methods including 1D and 2D nuclear magnetic resonance and high-resolution electrospray ionisation quadrupole-time of flight mass spectrometer spectrometry techniques are employed to determine their structures. Read more >
|Cat#||Product Name||Description||Recommended Medium||Price|
|CSC-7686W||adult stem cells||Bioarray, a pioneer in the adult stem cell fi...||-----||INQUIRY|
|CSC-7695W||Human Vertebral Mesenchymal Stem Cells (HVMSC)||Mesenchymal stem cells (MSC) are well-charact...||-----||INQUIRY|
|CSC-7700W||Human Umbilical Mesenchymal Stem Cells (HUMSC)||Mesenchymal stem cells (MSC) are a well-chara...||-----||INQUIRY|
|CSC-7725W||Human Pulmonary Mesenchymal Stem Cells (HPMSC)||Mesenchymal stem cells (MSC) are a well-chara...||-----||INQUIRY|
|CSC-7755W||Human Mesenchymal Stem Cells-hepatic (HMSC-he)||Mesenchymal stem cells (MSC) are well-charact...||-----||INQUIRY|
|CSC-7756W||Human Mesenchymal Stem Cells-bone marrow (HMSC-bm)||Mesenchymal stem cells (MSC) are well-charact...||-----||INQUIRY|
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