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Anxiolytic afobazole (5-Ethoxy-2-[2-(morpholino)-ethylthio]benzimidazole dihidrochloride) has pronounced ligand properties toward Sigma-1 receptor (σ1 receptor,SigmaR1) and MT 3 receptors. Our previous work demonstrated that afobazole possess cytoprotective effect in the in vitro model of menadione genotoxicity (Woods et al. Read more >
Aβ4-42 is a major species of Aβ peptide in the brains of both healthy individuals and those affected by Alzheimers disease. It has recently been demonstrated to bind Cu(II) with an affinity approximately 3000 times higher than the commonly studied Aβ1-42 and Aβ1-40 peptides, which are implicated in the pathogenesis of Alzheimers disease. Read more >
In a recent genome-wide association study, male reproductive ability was assessed for 7962 Fleckvieh sires (Pausch et al. 2014 PLoS Genet. 10, e1004044). Forty bulls in the population with exceptionally poor reproductive performance were found to be homozygous for a nonsense mutation in the transmembrane protein 95 (TMEM95)-encoding gene. Read more >
Metallothioneins (MTs) are low molecular weight proteins, which are present in almost all types of organisms. In mammals, four main MT isoforms designated from MT-1 to MT-4 were identified. Their biological role, according to their characteristic structure, was shown to be mostly associated with cellular metabolism of metal ions, especially zinc. Read more >
The activation of renin angiotensin system is involved in multiple pathological processes. The neuroprotective effect of propofol has been reported. We hypothesized that propofol may attenuate Angiotensin II (Ang II)-induced apoptosis in mouse hippocampal HT22 cells and aimed to identify the underlying mechanisms.
The cAMP/protein kinase A pathway regulates methamphetamine (METH)-induced neuroplasticity underlying behavioral sensitization. We hypothesize that adenylyl cyclases (AC) 1/8 mediate these neuroplastic events and associated striatal dopamine regulation. Locomotor responses to METH (1 and 5 mg/kg) and striatal dopamine function were evaluated in mice lacking AC 1/8 (DKO) and wild-type (WT) mice. Read more >
The divalent cation zinc is associated with cortical plasticity. However, the mechanism of zinc in the pathophysiology of cortical injury-associated neurobehavioral damage following neonatal seizures is uncertain. We have previously shown upregulated expression of ZnT-3; MT-3 in hippocampus of neonatal rats submitted to flurothyl-induced recurrent seizures, which was restored by pretreatment with ketogenic diet (KD). Read more >
We present a magneto-optic sensing system based on the "off-axis" optical probing technique to control the measurement sensitivity of magnets with various field strengths. The magnetic field is experimentally investigated in the absolute scale through a photonic calibration method with a standard electromagnet. Read more >
|Cat#||Product Name||Description||Recommended Medium||Price|
|CSC-6288W||MCF7-382||Species: human, Caucasian female 69 years old...||MEM + 10% FBS + 2mM L-Glutamine||INQUIRY|
|CSC-6289W||MCF7-422||Species: human, Caucasian female 69 years old...||MEM + 10% FBS + 2mM L-Glutamine||INQUIRY|
|CSC-6290W||MCF7-432||Species: human, Caucasian female 69 years old...||MEM + 10% FBS + 2mM L-Glutamine||INQUIRY|
|CSC-6291W||MCF7-488X1||Species: human, Caucasian female 69 years old...||MEM + 10% FBS + 2mM L-Glutamine||INQUIRY|
|CSC-6292W||MCF7-490X1||Species: human, Caucasian female 69 years old...||MEM + 10% FBS + 2mM L-Glutamine||INQUIRY|
|CSC-6293W||MCF7-492X1||Species: human, Caucasian female 69 years old...||MEM + 10% FBS + 2mM L-Glutamine||INQUIRY|
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