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MDA-MB-231

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-C8210L
  • Tissue of Origin
  • Breast
  • Description
  • This cell line was established from a pleural effusion of a 51 year old woman with metastatic breast cancer.
    Tumorigenecity: Yes, in nude mice also in ALS treated BALB/c mice; forms poorly differentiated adenocarcinoma(grade III)
    Isoenzyme: Me-2,1-2;PGM3,1;PGM1,1-2;ES-D,1;AK-1,1;GLO-1,2;G6PD B
    Histopathology: adenocarcinoma; pleural effusion
    Receptor Expression: epidermal growth factor (EGF), expressed; transforming growth factor alpha (TGF alpha), expressed
    Oncogene: The cells express the WNT7B oncogene
  • Organism
  • Homo sapiens, human
  • Morphology
  • Epithelial
  • STR DNA Profile
  • Amelogenin: X,X
    CSF1PO:12,13
    D13S317:13
    D16S539:12
    D5S818:12
    D7S820:8,9
    TH01:7,9.3
    TPOX:8,9
    vWA:15,19
    D3S1358: 16
    D21S11: 30,33.2
    D18S51: 11,16
    Penta E: 11
    Penta D: 11,14
    D8S1179: 13
    FGA: 22,23
  • Culture Properties
  • Monolayer, adherent
  • Karyotype
  • Mean chromosome number = 68; (P17), hypotriploid with abnormalities including breaks, secondary constrictions and fragmentations
  • Source
  • Breast (pleural effusion)
  • Quality Control
  • Fluorescence (DAPI) test: negative; Mycoplasma specific PCR: negative; Bacteria specific PCR: negative
  • Storage and Shipping
  • liquid nitrogen vapor phase
  • Application
  • This cell line is a suitable transfection host.
  • Disease
  • adenocarcinoma

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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
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      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com