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A series of nucleolipids, containing one of the β-D-ribonucleosides 5-fluorouridine, 6-azauridine, uridine, or 5-methyluridine were lipophilized, either at the O-2,3-position and/or at N(3) of the nucleobase with a large variety of hydrophobic residues. The resulting nucleolipids as well as the parent nucleosides and the lipid precursors were investigated in vitro with respect to their antitumor activity towards i) ten human tumor cell lines from the NCI 60 panel and ii) partly against three further tumor cell lines, namely a) human astrocytoma/oligodendro glioma GOs-3, b) rat malignantneuroectodermal BT4Ca, and c) differentiated human THP-1 macrophages. Read more >
Attempts to clarify mechanisms of early brain injury in subarachnoid hemorrhage (SAH) revealed a high-mobility group box 1 (HMGB1) protein involvement in sterile inflammation initiated by aneurysm rupture. This study aims at assessing the prognostic value of HMGB1 in comparison with traditional biomarkers.
Here, we aimed to evaluate the experience of transsylvian-transinsular microsurgical approach (TTH) to the huge lateral thalamic hemorrhages (THs). A total of 37 patients with huge lateral TH (hematoma volumes between 30 and 90 cm) who underwent surgical treatment through middle or distal TTH at the Bayi Brain Hospital from January 2007 to May 2012 were included in this series. Read more >
Intracerebral hemorrhage (ICH) volume, particularly if ≥30 mL, is a major determinant of poor outcome. We used a multinational ICH data registry to study the characteristics, course, and outcomes of supratentorial hematomas with volumes <30 mL.
Severe traumatic brain injury (TBI) is the predominant cause of death and disability following trauma. Several studies have observed improved survival in TBI patients exposed to β-blockers, however, the effect on functional outcome is poorly documented.
The aim of our study was to assess the functional outcome of brain injury (BI) victims and to review the impact of treatment time on functional abilities.
To investigate the association between positive blood alcohol level (BAL) and functional outcome in patients suffering severe traumatic brain injury.
We have previously described a method that has the potential to improve surgery of arteriovenous malformations (AVMs). In the present paper, we present our clinical results.
|Cat#||Product Name||Description||Recommended Medium||Price|
|CSC-C0317||LN-405||Glioblastoma cells established from an astroc...||90% DMEM + 10% h.i. FBS||INQUIRY|
|CSC-C0377||U-138 MG; U-138-MG||This is one of a number of cell lines derived...||DMEM supplemented with 4.5g/L glucose, 2mM gl...||INQUIRY|
|CSC-C0391||SNB-19||Established from the surgical resection of a ...||90% DMEM + 10% h.i. FBS||INQUIRY|
|CSC-C9434L||HS-683;Hs 683||Hs 683 cells were isolated from explant cultu...||DMEM supplemented with 4.5 g/L glucose, 2 mM ...||INQUIRY|
|CSC-C8781H||CCF-STTG1||-----||RPMI-1640 supplemented with 4.5g/L glucose, 2...||INQUIRY|
|CSC-C8881H||NCH421K||The NCH421K cell line was established by Chri...||Chemically defined serum free medium.||INQUIRY|
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