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In search of novel cytotoxic agents based on acridone scaffold, twenty five derivatives of acridone-2- carboxamide were synthesized and evaluated against a panel of eleven cancer cell lines by using MTT assay. Amides, A5 and A8 (IC50 = 0.3 µM) exhibited good cytotoxicity against MCF7. Compound A22 (IC50 = 4. Read more >
Nitric oxide (NO) is an intracellular and intercellular messenger involved in numerous physiological and pathophysiological processes. Small-molecule fluorescent probes coupled with fluorescence microscopy provide excellent tools for real-time detection of NO in situ. However, most probes are designed for imaging intracellular NO, which cannot reflect the release behavior of endogenously produced NO. Read more >
Porphyromonas gingivalis has been shown to actively invade endothelial cells and induce vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1) overexpression. Nucleotide-binding oligomerization domain 1 (NOD1) is an intracellular pattern recognition reporter, and its involvement in this process was unknown. Read more >
Protein tyrosine phosphorylation is an important mechanism that regulates cytoskeleton reorganization and cell spreading of migratory cells. A number of cytoskeletal proteins are known to be tyrosine phosphorylated (pY) in different cellular processes. However, the profile of pY proteins during different stages of cell spreading has not been available. Read more >
The aim of the research was to investigate cytotoxicity of fucoidans on mammals cells. Three different samples of fucoidans were isolated from mechanically grounded brown algae Laminaria digitata and Fucus ve- siculosus. The sample F2 that differed from the others by higher sulfatation level and suppression of HeLa G-63 line culture growth was taken for further study in cell lines HeLa G-63, ECV 304 and PC 12. Read more >
This work aims to investigate the treatment effect of endostatin (ES) in the nude mouse model with endometriosis (EMs).
To investigate if Ad-NK4 can enhance the chemosensitivity of human multiple myeloma RPMI 8226 cells to bortezomib(BOR).
To study the inhibition of berberine (BBR) against ECV-304 apoptosis induced by Staphylococcus aureus (S. aureus).
|Cat#||Product Name||Description||Recommended Medium||Price|
|CSC-C0268||RT-112||Established from the transitional cell carcin...||RPMI-1640 medium supplemented with 2 mM L-glu...||INQUIRY|
|CSC-C0334||BT-B||These cells were thought to be "stablished fr...||90% RPMI-1640 + 10% h.i. FBS||INQUIRY|
|CSC-C0335||SBC-2||These cells were thought to be "established f...||90% RPMI-1640 + 10% h.i. FBS||INQUIRY|
|CSC-C0336||SBC-7||These cells were thought to be "established f...||90% RPMI-1640 + 10% h.i. FBS + 2 mM L-glutami...||INQUIRY|
|CSC-C0413||BFTC-905||Established from a 51-year-old Chinese woman ...||80-90% DMEM + 10-20% h.i. FBS||INQUIRY|
|CSC-C0424||T24;T-24||Established from the primary tumor of an 81-y...||DMEM:Ham's F12 medium (1:1 mixture) supplemen...||INQUIRY|
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