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BEN-MEN-1

  • Specification
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Cat.No.
CSC-C1388
Description
Established in 2003 from the meningothelial meningioma (grade I, WHO, #1238-03) attached to the parietal falx of a 68-year-old woman after surgical tumor resection; cells were immortalized by retroviral transduction with human telomerase reverse transcriptase (hTERT)
Species
Human
Source
benign meningioma
Recommended Medium
80% DMEM + 20% h.i.FBS
Culture Properties
monolayer
Morphology
adherent, epithelial cells growing as monolayers
Karyotype
Human hypodiploid karyotype with 12% polyploidy; 44(43-46)<2n>XX, -22; frequent random chromosome loss; monosomy 22 is recurrent in grade I benign meningiomas; matches published karyotype
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: cytokeratin-7 +, cytokeratin-8 -, cytokeratin-17 -, cytokeratin-18 +, cytokeratin-19 -, desmin -, endothel -, EpCAM -, GFAP -, neurofilament -, vimentin +
Viruses: PCR: EBV -, HBV -,
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 1-2 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
CM-1010X

For research use only. Not for any other purpose.

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Q:
What are the potential challenges in quality control of tumor cells, and how can they be mitigated?
A:

Challenges include cross-contamination, misidentification, and genetic drift. These can be addressed through authentication, regular testing, and strict culture management.

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Average Rating: 5.0    |    1 Scientist has reviewed this product

Valuable tool for drug discovery

As a researcher focusing on cancer therapeutics, I found the tumor cell product to be an invaluable tool for drug discovery. The cells responded consistently to various treatments, allowing me to evaluate the efficacy of potential drug candidates.

04 Jan 2024


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