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ActoFactor™ Recombinant Mouse Interleukin 16

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0693
  • Description
  • IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of IL-16 is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. Major IL-16 functions are exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase-3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene.IL-16 stimulates a migratory response in cd4+ lymphocytes, monocytes, and eosinophils and it also induces t-lymphocyte expression of interleukin-2 receptor ligand for cd4.|Recombinant mouse IL-16 produced in E. coli is a single, non-glycosylated polypeptide chain of 127 amino acids having a molecular mass of 13.2 kDa. It has been purified by using proprietary chromatographic techniques.
  • Species
  • Mouse
  • Product Overview
  • Mouse Il16 expressed in E.coli
  • Molecular Mass
  • 13.2 kDa
  • Size
  • CAT# CSC-CTK0693-10 (10 μg); CAT# CSC-CTK0693-50 (50 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 90% as determined by SDS-PAGE and RP-HPLC analysis.
  • Activity
  • N/A
  • Endotoxin Level
  • N/A
  • Formulation
  • Lyophilized from a concentrated (1 mg/ml), sterile- filtered protein solution after extensive dialysis against 10 mM sodium phosphate buffer (pH 7.5).
  • Reconstitution
  • Please centrifuge product briefly before opening the vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at –20°C for future use.
  • Storage & Stability
  • The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored dessicated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at –20°C. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze / thaw cycles.

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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
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      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com