Online Inquiry & Support

USA: 1-631-626-9181   Fax: 1-631-614-7828
Europe: 44-207-097-1828

ActoFactor™ Recombinant Mouse Defensin beta 2

Bookmark and Share
  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0733
  • Description
  • Defensins are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. To date, four human beta-defensins have been identified: BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on leukocytes and at epithelial surfaces and are 3-5 kDa peptides consisting of 33-47 amino acid residues. Human BD- 1 is down-regulated in human prostatic and renal carcinomas. Skin of patients having atopic dermatitis and mycosis fungoides (non-lesional and lesional) show lower human BD-1 mRNA expression and higher human BD-2 and BD-3 mRNA expression. The level of expression of human BD-1 mRNA is also lower than that of human BD3 and human BD-2 in reconstructed epidermis. Creative Bioarrays recombinant human beta-Defensin-2 (rHu BD-2) produced in E. coli is a single, non-glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5.5 kDa. It has been purified by proprietary chromatographic techniques.
  • Species
  • Mouse
  • Product Overview
  • Mouse Defb2 expressed in E.coli
  • Molecular Mass
  • 5.5 kDa
  • Size
  • CAT# CSC-CTK0733-20 (20 μg); CAT# CSC-CTK0733-100 (100 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 98% as determined by SDS-PAGE and HPLC analysis.
  • Activity
  • Determined by the ability to chemoattract immature human dendritic cells at a concentration of 10-100 ng/ml.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • Lyophilized from a sterile-filtered (0.2 μm) concentrated protein solution in PBS (pH 7.4).
  • Reconstitution
  • Please centrifuge product before opening the vial. The lyophilized protein should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • The lyophilized BD-2, though stable at room temperature, is best stored desiccated at -20°C. Reconstituted BD-2 should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze / thaw cycles.
  • Official Symbol
  • Defb2

Citation Guidance:
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.

Price Inquiry

Please input "bioarray" as verification code.


tissue samples, tissue arrays, cells, microorganisms, probes and services for your research.



Contact Us
    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Tel: 44-207-097-1828
Ordering Information
    • Payment methods we support:
      ✭ Invoice / Purchase Order
      ✭ Credit card
Contact Us
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828

Tel: 44-207-097-1828