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ActoFactor™ Recombinant Human Selectin P (granule membrane protein 140kDa, antigen CD62)

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0652
  • Description
  • P-selectin also called Platelet Alpha-Granule Membrane Protein, CD62, or Granulocyte Membrane Protein GRMP belongs to a family of divalent cation-dependent carbohydrate- binding glycoproteins or adhesion molecules. P-selectin is expressed transiently on the surface of activated platelets and endothelial cells. P-selectin is a 140 kDa protein which is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Secreted P-selectin is thought to play a key role in the adhesion of platelets to monocytes and neutrophils during an inflammatory response. P-selectin is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Levels of P-selectin may be elevated in a number of pathological conditions.|Human recombinant P-selectin produced in E. coli contains 566 amino acids 197-761 which are fused to an amino-terminal hexa-histidine tag.
  • Species
  • Human
  • Product Overview
  • Human SELP expressed in E.coli
  • Molecular Mass
  • 140 kDa
  • Size
  • CAT# CSC-CTK0652-10 (10 μg); CAT# CSC-CTK0652-50 (50 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 95% as determined by SDS-PAGE analysis.
  • Activity
  • N/A
  • Endotoxin Level
  • N/A
  • Formulation
  • Sterile-filtered, liquid formulation. P-selectin is supplied in 50% glycerol.
  • Reconstitution
  • Please centrifuge product briefly before opening vial. The protein solution can be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • For long-term storage, protein solution should be stored at -20°C. Avoid repeated freeze / thaw cycles.

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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
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      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com