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ActoFactor™ Recombinant Human Myostatin (E. coli)

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0467
  • Description
  • Recombinant Human Myostatin (rHu Myostatin) is a TGF-beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin. Recombinant Human Myostatin is a 25.0 kDa protein consisting of two identical 109 amino acid polypeptides linked by a single disulfide bond.
  • Species
  • Human
  • Product Overview
  • Human MSTN expressed in E.coli
  • Molecular Mass
  • 25.0 kDa
  • Size
  • CAT# CSC-CTK0467-10 (10 μg); CAT# CSC-CTK0467-50 (50 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 95% as determined by SDS-PAGE, FPLC and HPLC analysis.
  • Activity
  • The biological activity of Myostatin was determined by its ability to inhibit the proliferation of MPC-11 cells. The ED50 for this effect is < 20.0 ng/ml.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • The sterile-filtered protein solution was lyophilized with no additives.
  • Reconstitution
  • Please centrifuge product before opening the vial. The lyophilized protein should be reconstituted in sterile 20 mM HCl to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • The lyophilized powder, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted Myostatin should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze / thaw cycles.

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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
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      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com