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ActoFactor™ Recombinant Human Matrix metallopeptidase 2 (HEK)

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0369
  • Description
  • Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up- regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant human MMP-2 produced in HEK293 cells is a proform of the Human MMP-2 (Ala30-Cys660) and fused with a ployhistide tag at the C-terminus, having a MW of 71kDa.
  • Species
  • Human
  • Product Overview
  • Human MMP2 expressed in HEK cells
  • Molecular Mass
  • 71 kDa
  • Size
  • CAT# CSC-CTK0369-10 (10 μg); CAT# CSC-CTK0369-50 (50 μg)
  • Expression System
  • HEK cells
  • Purity
  • Greater than 95% as determined by SDS-PAGE.
  • Activity
  • The activity was measured by its ability to cleave the colorimetric peptide substrate Mca-PLGL- DpaAR-NH2. The specific activity is > 1,000 pmoles/min/μg.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • The MMP-2 is supplied as a 0.2μm filtered solution in Tris, NaCl and Brij35.
  • Reconstitution
  • Please centrifuge product briefly before opening vial. The protein solution can be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. Can also be used as standard in Western blot, etc.

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    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com