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ActoFactor™ Recombinant Human Interleukin 19

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0266
  • Description
  • IL-19 is a cytokine that belongs to the IL10 cytokine subfamily. IL-19 is found to be preferentially expressed in monocytes. It can bind the IL-20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. Interleukin-19 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids and having a molecular mass of 17913 Dalton.
  • Species
  • Human
  • Product Overview
  • Human IL19 expressed in E.coli
  • Molecular Mass
  • 17.9 kDa
  • Size
  • CAT# CSC-CTK0266-10 (10 μg); CAT# CSC-CTK0266-50 (50 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 99% as determined by SDS-PAGE and RP-HPLC analysis.
  • Activity
  • The activity is determined by its ability to activate STAT following receptor-ligand interaction.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • Lyophilized steril-filtered protein from a concentrated (1mg/ml) solution in water containing 10mM sodium citrate pH-5.
  • Reconstitution
  • Please centrifuge product briefly before opening vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted rHu IL-19 should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.

Citation Guidance:
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.

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    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com