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ActoFactor™ Recombinant Human Interleukin 16 (130 aa variant)

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0257
  • Description
  • Recombinant Human Interleukin 16 (rHu IL-16) is a CD8+ T-cell-derived cytokine that induces chemotaxis of CD4+ T-cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T-cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 13.5 kDa protein consisting of 130 amino acid residues.
  • Species
  • Human
  • Product Overview
  • Human IL16 expressed in E.coli
  • Molecular Mass
  • 13.5 kDa
  • Size
  • CAT# CSC-CTK0257-10 (10 μg); CAT# CSC-CTK0257-50 (50 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 98% as determined by SDS-PAGE and HPLC analysis.
  • Activity
  • The biological activity of rHu IL-16 was determined by its ability to chemoattract human CD4+ T- Lymphocytes using a concentration range of 1.0-100.0 ng/ml.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • The sterile-filtered solution was lyophilized with no additives.
  • Reconstitution
  • Please centrifuge product briefly before opening the vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • The lyophilized powder, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted IL-16 should be used immediately or stored long-term in undiluted working aliquots at -20°C. Avoid repeated freeze/thaw cycles.

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    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com