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ActoFactor™ Recombinant Human Hepatocyte Growth Factor, A Chain

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0415
  • Description
  • Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69 kDa Alpha chain and 34 kDa Beta chain. A disulfide bond linking the alpha and beta chains produces the active, heterodimeric molecule. Human recombinant HGF-A produced in E. coli is a single, non-glycosylated, polypeptide chain containing a 463 amino acids fragment (32-494) and having a molecular weight of 69 kDa. It is fused with a 4.5 kDa amino-terminal hexahistidine tag.
  • Species
  • Human
  • Product Overview
  • Human HGF expressed in E.coli
  • Molecular Mass
  • N/A
  • Size
  • CAT# CSC-CTK0415-10 (10 μg); CAT# CSC-CTK0415-50 (50 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 95% as determined by SDS-PAGE analysis.
  • Activity
  • N/A
  • Endotoxin Level
  • N/A
  • Formulation
  • Sterile-filtered, clear protein solution (0.105 mg/m l) in 22 mM sodium acetate (pH 4.8), 1 mM EDTA and 50% glycerol.
  • Reconstitution
  • Please centrifuge product briefly before opening vial. The dissolved protein can be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • Store at 4°C if entire vial will be used within 4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

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    • USA
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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com