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ActoFactor™ Recombinant Human Collagen, type XVIII, alpha 1

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0614
  • Description
  • Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin produced in Pichia Pastoris is a single, glycosylated polypeptide consisting of 184 amino acid residues and having a total molecular mass of 20,000 Dalton. is a 20.2 kDa protein. The Endostatin was purified using proprietary chromatographic techniques.
  • Species
  • Human
  • Product Overview
  • Human COL18A1 expressed in Pichia pastoris
  • Molecular Mass
  • 20.2 kDa
  • Size
  • CAT# CSC-CTK0614-100 (100 μg); CAT# CSC-CTK0614-500 (500 μg)
  • Expression System
  • Pichia pastoris
  • Purity
  • Greater than 98% as determined by SDS-PAGE and HPLC analysis.
  • Activity
  • The activity calculated by ECE migration inhibition was found to be 50,000IU/mg.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • Sterile filtered liquid formulation 5 mg/ml in PBS.
  • Reconstitution
  • N/A
  • Storage & Stability
  • The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored dessicated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at –20°C. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze / thaw cycles.

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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
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      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com