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ActoFactor™ Recombinant Human CD4 molecule

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0109
  • Description
  • CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV. Thymocytes which are CD4 (+) and CD8 ( - ) produce factors such as IL-4, IL-5, IL-10 and IFN-gamma. Recombinant Human sCD4 produced in Baculovirus is a single, glycosylated polypeptide chain of 365 amino acids and a non-glycosylated molecular mass of 45,000 Dalton. As a result of glycosylation, the sCD4 migrates as a 46,000 Dalton protein on standard SDS-PAGE.
  • Species
  • Human
  • Product Overview
  • Human CD4 expressed in Baculovirus
  • Molecular Mass
  • 45 kDa
  • Size
  • CAT# CSC-CTK0109-10 (10 μg); CAT# CSC-CTK0109-50 (50 μg)
  • Expression System
  • Baculovirus
  • Purity
  • Greater than 90% as determined by SDS-PAGE and RP-HPLC analysis.
  • Activity
  • Recombinant human sCD4 is immune-reactive using monoclonal anti-CD4 antibodies in an gpl2O capture ELISA assay.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • The sterile-filtered, colourless sCD4 solution contains 10 mM sodium phosphate buffer (pH 7.0) and 300 mM sodium chloride.
  • Reconstitution
  • Please centrifuge product briefly before opening vial. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • Store at 4°C if the entire vial will be used within 1 week. Store, frozen at -20°C for longer periods of time. Avoid repeated freeze-thaw cycles.

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    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com