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A2780/cis
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Cat.No.
CSC-C9492J
Description
This cisplatin-resistant cell line has been developed by chronic exposure of the parent cisplatin-sensitive A2780 cell line to increasing concentrations of cisplatin. A2780cis is cross-resistant to melphalan, adriamycin and irradiation. An increased ability to repair DNA damage as well as cytogenetic abnormalities has been observed. In order to retain resistance cisplatinum has to be added to the media for every passage. In addition to this matched pair of drug-sensitive/resistant cell lines an adriamycin-resistant cell line, A2780adr, has been isolated from the same parental line A2780.
Species
Human
Source
Reproductive: Ovary
Recommended Medium
RPMI 1640 + 2mM Glutamine + 1µM cisplatinum + 10% Foetal Bovine Serum (FBS) .
Culture Properties
Adherent
Morphology
Epithelial
Storage and Shipping
Creative Bioarray ships frozen cells on dry ice. On receipt, immediately transfer frozen cells to liquid nitrogen (-180 °C) until ready for experimental use.
Never can cryopreserved cells be kept at -20 °C.
Never can cryopreserved cells be kept at -20 °C.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
What are the common characteristics of ovarian cancer cells?
A:
Ovarian cancer cells often exhibit characteristics such as uncontrolled growth, the ability to invade nearby tissues, resistance to cell death (apoptosis), and the potential to spread (metastasize) to other organs.
Average Rating: 4.0 | 1 Scientist has reviewed this product
Good
The product was surprisingly frozen well, with minimal cell death observed during storage.
21 May 2023
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